Human Monocyte Interleukin-1β Posttranslational Processing
نویسندگان
چکیده
منابع مشابه
Human monocyte stimulus-coupled IL-1β posttranslational processing: modulation via monovalent cations.
Lipopolysaccharide-activated human monocytes produce prointerleukin (pro-IL)-1β but release little of this inflammatory cytokine as the biologically active species. Efficient externalization of mature 17-kDa cytokine requires that the activated monocytes encounter a secondary stimulus such as ATP. To identify cation requirements of the ATP-induced process, lipopolysaccharide-activated monocytes...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1996
ISSN: 0021-9258
DOI: 10.1074/jbc.271.47.29830